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Irresistible Spicy Southern Chicken Spaghetti Casserole

Irresistible Spicy Southern Chicken Spaghetti Casserole in 30 Minutes

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A flavorful and spicy chicken spaghetti casserole with Southern-inspired flavors.

  • Total Time: 45 mins
  • Yield: 6 servings 1x

Ingredients

Scale
  • 2 cups cooked chicken, shredded
  • 8 oz spaghetti, cooked
  • 1 can (10.5 oz) cream of chicken soup
  • 1 cup diced tomatoes with green chilies
  • 1 cup shredded cheddar cheese
  • 1/2 cup sour cream
  • 1/2 cup chicken broth
  • 1 tsp garlic powder
  • 1 tsp onion powder
  • 1/2 tsp cayenne pepper
  • Salt and black pepper to taste

Instructions

  1. Preheat oven to 350°F.
  2. Mix chicken, spaghetti, soup, tomatoes, sour cream, broth, and spices in a bowl.
  3. Transfer mixture to a greased baking dish.
  4. Sprinkle cheese on top.
  5. Bake for 25-30 minutes until bubbly.
  6. Let cool briefly before serving.

Notes

  • Adjust cayenne pepper for preferred spice level.
  • Substitute rotisserie chicken for convenience.
  • Store leftovers refrigerated for up to 3 days.
  • Author: Lisa
  • Prep Time: 15 mins
  • Cook Time: 30 mins
  • Category: Casserole
  • Method: Baked
  • Cuisine: Southern
  • Diet: Low Lactose

Nutrition

  • Serving Size: 1 cup
  • Calories: 420
  • Sugar: 4g
  • Sodium: 780mg
  • Fat: 18g
  • Saturated Fat: 8g
  • Unsaturated Fat: 7g
  • Trans Fat: 0g
  • Carbohydrates: 38g
  • Fiber: 3g
  • Protein: 25g
  • Cholesterol: 75mg